Uncaria hook

Ingredient Profile

Modern Research Perspective

Uncaria Hook contains indole alkaloids including rhynchophylline and isorhynchophylline. Cell and animal studies have examined vascular, blood-pressure, neuronal, anti-inflammatory, and antioxidant mechanisms. These findings are preclinical and depend on species, extraction, and alkaloid content.

Human clinical evidence for a standardized single material is limited. Effects on blood pressure and interactions with cardiovascular or sedative medicines require attention, while dose, pharmacokinetics, and long-term safety remain incompletely defined.

Traditional Function

In traditional Chinese medicine, Uncaria Hook is sweet and slightly cold. It is used to calm the Liver, extinguish internal wind, and clear heat. Its use is interpreted according to rising Liver yang, dizziness, headache, tremor, or wind-related patterns.