Efficacy and Safety of SanJieZhenTong Capsules: A Randomized Controlled Trial
Citation
Ruan JY, Zheng YX, Tian Q, et al. Efficacy and Safety of SanJieZhenTong Capsules, a Traditional Chinese Patent Medicine, on Long-term Management of Endometriosis: A Randomized Controlled Trial. Reproductive and Developmental Medicine. 2021;5(1):15–22. DOI: 10.4103/2096-2924.313687.
| Authors | Ruan JY, Zheng YX, Tian Q, et al. |
|---|---|
| Publication Year | 2021 |
| Journal | Reproductive and Developmental Medicine |
| DOI | 10.4103/2096-2924.313687 |
Study Details
| Study Design | Randomized controlled trial |
|---|---|
| Evidence Level | Limited human evidence |
| Population | Women with stage III-IV endometriosis after conservative laparoscopic surgery and three initial GnRH-a doses. |
| Sample Size | 66 |
| Intervention | Sanjie Zhentong Capsule for 6 months after initial postoperative GnRH-a treatment. |
| Comparator | Continued GnRH-a or oral contraceptive therapy. |
Outcomes
Symptomatic recurrence, pain, quality of life, sexual function, organ function, costs, and adverse events.
Results
Recurrence and pain outcomes did not differ significantly among groups; some treatment-associated symptoms were reported less often than with continued GnRH-a.
Limitations
Small sample; only 21 participants received the capsule; all participants had surgery and initial GnRH-a treatment; the study stopped below its planned enrollment.